Opioid Analgesics Are More Dangerous For Health Than The Non-Opioid Analgesics.
Two redone studies suggest that Medicare patients who pick opioid painkillers such as codeine, Vicodin or Oxycontin impression higher fettle risks, including death, sensitivity problems or fractures, compared to those taking non-opioid analgesics. However, it's not unimpeded if the painkillers are without delay responsible for the differences in risk, experts said, and other factors could entertainment a role good tips for selling a car on auction. And one pain specialist who's familiar with the findings said they don't display the experiences of doctors who've prescribed the drugs.
In one study, researchers examined a database of Medicare recipients in two states who were prescribed one of five kinds of opiod painkillers from 1996-2005. They looked at almost 6,300 patients who took one of these five painkillers: codeine phosphate, hydrocodone bitartrate (best known in its Vicodin form), oxycodone hydrochloride (Oxycontin), propoxyphene hydrochloride (Darvon), and tramadol hydrochloride (Ultram). Those who took codeine were 1,6 times more in all probability to have suffered from cardiovascular problems after 180 days, while patients on hydrocodone seemed to be at higher hazard of fractures than those who took tramadol and propoxyphene.
After 30 days, those who took oxycodone were 2,4 times more qualified to want than those taking hydrocodone, and codeine users were twice as like as not to die, although the crowd of deaths was small. The muse about authors discretion that their findings are surprising in some ways and exigency to be confirmed by further research. Commenting on the study, Dr Russell K Portenoy, chairman of the part of trial panacea and palliative heedfulness at Beth Israel Medical Center in New York City, said that the findings are of predetermined value because many other factors could spell out the differences between the drugs, such as how express physicians ramped up the doses of patients.
