Malignant Brain Tumors In Children Will Soon Be Able To Be Curable.
A prelude bone up has found that a targeted remedying for medulloblastoma - the most conventional malignant brain cancer in children - may one age be able to treat drug-resistant forms of the disease. "Less than 5 percent of patients currently pull through medulloblastoma," said Dr Amar Gajjar, create author of the study, which was presented Saturday at the annual meet of the American Society of Clinical Oncology (ASCO) in Chicago medicine. "Most patients by and large die 12 to 18 months after the tumor comes back".
Although this den was designed basically to assess side effects, if the drug moves through the pharmaceutical pipeline, it would be the start targeted drug aimed at a signaling pathway. Chemotherapy is the crucial treatment now. The drug, known as GDC-0449, interrupts the "sonic hedgehog" pathway, which has been implicated in a legions of other cancers; it is interested in 20 percent of cases of children with medulloblastoma.