Austrian Scientists Have Determined The Effect Of Morphine On Blood Coagulation

Austrian Scientists Have Determined The Effect Of Morphine On Blood Coagulation.
Morphine appears to curtail the effectiveness of the commonly second-hand blood-thinning hallucinogen Plavix, which could shackle emergency-room efforts to treat heart vilify victims, Austrian researchers report. The finding could forge serious dilemmas in the ER, where doctors have to weigh a determination patient's intense pain against the need to break up and prevent blood clots, said Dr Deepak Bhatt, superintendent supervisor of interventional cardiovascular programs at Brigham and Women's Hospital Heart and Vascular Center, in Boston neosize xl official site bangkok. "If a philosophical is having crushing soul pain, you can't just tell them to tough it out, and morphine is the most commonly hand-me-down medication in that situation," said Bhatt, who was not snarled in the study.

And "Giving them morphine is the humane trend to do, but it could also create delays in care". Doctors will have to be particularly watchful if a heart attack patient needs to have a stent implanted. Blood thinners are perilous in preventing blood clots from forming around the stent. "If that state is unfolding, it requires a little iota of extra thought on the part of the physician whether they want to give that full slug of morphine or not".

About half of the 600000 stent procedures that swipe domicile in the United States each year occur as the result of a nature attack, angina or other acute coronary syndrome. The Austrian researchers focused on 24 thriving people who received either a quantity of Plavix with an injection of morphine or a placebo drug. Morphine delayed the capacity of Plavix (clopidogrel) to thin a patient's blood by an norm of two hours, the researchers said.

Morphine Can Protect The Brains Of People Suffering From HIV Infection

Morphine Can Protect The Brains Of People Suffering From HIV Infection.
The anaesthetic morphine may relief care for against HIV-associated dementia, says a imaginative study 4rxbox com. Georgetown University Medical Center researchers found that morphine protected rat neurons from HIV toxicity, a origination that could manage to the development of new drugs to treat kinsfolk with HIV-related dementia, which causes depression, anxiety and physical and barmy problems.

So "We believe that morphine may be neuroprotective in a subset of individuals infected with HIV," lead investigator Italo Mocchetti, a professor of neuroscience, said in a Georgetown information release. He and his colleagues conducted the den because they knew that some people with HIV who are heroin users never bare HIV brain dementia. Morphine is like to heroin.

In their tests on rats, the researchers found that morphine triggers imagination cells called astrocytes to produce a protein called CCL5, which activates factors that censor HIV infection in exempt cells. CCL5 "is known to be important in blood, but we didn't identify it is secreted in the brain," Mocchetti said. "Our premise is that it is in the brain to prevent neurons from dying".

The read was to be presented at the annual meeting of the Society of NeuroImmune Pharmacology, April 13 to 17 in Manhattan Beach, Calif. "Ideally, we can use this news to strengthen a morphine-like compound that does not have the typical dependency and clearance issues that morphine has," Mocchetti said.