Alzheimer's Disease Is Associated With A High Blood Pressure

Alzheimer's Disease Is Associated With A High Blood Pressure.
People misery from cardiovascular ailment who have lower-than-normal blood arm may face a higher chance of brain atrophy - the death of brain cells or connections between thought cells, Dutch researchers report June 2013. Such knowledge atrophy can lead to Alzheimer's malady or dementia in these patients provillus. In contrast, similar patients with extreme blood pressure can slow brain atrophy by lowering their blood pressure, the researchers added.

Blood force is measured using two readings. The surmount number, called systolic pressure, gauges the compression of blood moving through arteries. The bottom number, called diastolic pressure, measures the intimidate in the arteries between heartbeats. Normal blood make for adults is less than 120/80, according to the US National Heart, Lung, and Blood Institute.

For the study, 70 to 90 was considered healthy diastolic blood pressure, while under 70 was considered low. "Our details might suggest that patients with cardiovascular disorder assert a subgroup within the general population in whom low diastolic blood weight might be harmful," said researcher Dr Majon Muller, an epidemiologist and geriatrician at VU University Medical Center in Amsterdam.

On the other hand, lowering blood squeezing in mortals with great in extent blood pressure might slow brain atrophy. "Our findings could indicate that blood pressure lowering is serviceable in patients with higher blood pressure levels, but one should be cautious with further blood tension lowering in patients who already have low diastolic blood pressure".

The make public was published in the June 10 online print run of JAMA Neurology. A US expert noted the complex gear of blood pressure levels on the brain. "High blood put the screws on has been shown to increase the risk of vascular brain lesions and perception atrophy. Trials of blood pressure lowering in patients with hypertension have shown reduced danger of brain lesions," said Dr Gregg Fonarow, a professor of cardiology at the University of California, Los Angeles, and a spokesman for the American Heart Association.

However, in patients with hypertension, the relation between the levels of systolic and diastolic blood prevail upon and understanding atrophy has been less clear. This immature ponder suggests that low diastolic blood pressure levels were associated with brains atrophy regardless of blood pressure levels after patients developed dementia. "These findings suggest that while healing and sway of high blood pressure is very important for brain and cardiovascular health, vigilance is needed in patients who have low diastolic blood insist upon levels".

To see what changes blood pressure would enact in the progression of brain atrophy, Muller's group studied 663 patients who suffered from sincerity disease, cardiovascular disease, secondary artery disease or abdominal aortic aneurysm. The typical age of participants was 57 and most were men. People whose diastolic blood turn the heat on was below 70 had more brain atrophy over time, the investigate found.

For people with higher-than-normal blood pressure, acumen atrophy decreased when their blood pressure did. When blood intimidation rose, however, atrophy increased. Another expert, Dr Sam Gandy, associate director of the Mount Sinai Alzheimer's Disease Research Center in New York City, said that the declaration "is an substantial cautionary tale".

This implies that one must suit the approach to the individual patient. Correction of hypertension is helpful, but reducing blood lean on in patients with usual blood pressure is risky and complicated" vitomol.eu. Although the lessons found an association between low diastolic blood pressure and the risk of developing genius atrophy for people with artery disease, it did not establish a cause-and-effect relationship.